Strain Information

Name SZ370   View On Wormbase
Species C. elegans
Genotypesnu-66(az160) V.
DescriptionSNU-66 H765G substitution. No obvious morphological or growth phenotypes were observed. az160 mutation disrupts SNU-66(H765)/SNRP-27(M141) interaction, affecting alternative 5' splice site usage. Worm SNU-66(H765) and SNRP-27(M141) are homologous to human preB spliceosome components snu66(H734) and snrnp27(M141), respectively. Reference: Sarka K, et al. 2024. In submission.
Made byKenna Sarka
Laboratory SZ
Reference Sarka, K., Katzman, S. and Zahler, A.M. 2024. A Role for SNU66 in Maintaining 5’ Splice Site Identity During Spliceosome Assembly. Submitted to RNA Journal.
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