Strain Information

Name SV2071   View On Wormbase
Species C. elegans
Genotypehe317[eft-3p::Lox2272::egl-13-NLS::tagBFP2::let-858 3'UTR::Lox2272::egl-13-NLS::mCherry::let-858 3'UTR] IV; heSi220 X.
DescriptionheSi220 [lin-31p::Cre] X. Vulval lineage is marked through activity of a Cre-dependent reporter (blue-to-red switch). All cells in the animal are expressing BFP, except for vulval cells which are expressing mCherry. he317 was inserted into the cxTi10816 site using CRISPR/Cas9. Reference: van der Vaart A, et al. Sci. Adv. 2020 May; 6(21): eaay3823. PMID: 32494730.
MutagenCrispr/Cas9
Outcrossedx0
Made byVincent Portegijs
Laboratory SV
Reference Van Der Vaart, Aniek, Godfrey, Molly, Portegijs, Vincent & Van Den Heuvel, Sander (20-05-2020). Dose-dependent functions of SWI/SNF BAF in permitting and inhibiting cell proliferation in vivo. Science advances, 6 (21) (15 p.)
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