Strain Information

Name SV1930   View On Wormbase
Species C. elegans
Genotypeswsn-8(he273 he287 [LoxN exon 3 + LoxN last intron]) I; heSi208 V; heSi141 X.
DescriptionheSi208 [eft- 3p::LoxP::NLS(egl-13)::tagBFP2::tbb-2 UTR::LoxP::NLS(egl-13)::mCherry::tbb-2 3'UTR] V. heSi141 [hlh-8p::CRE] X. he273 he287 homozygotes are Egl since they cannot form a functioning vulva due to swsn-8 inactivated in the mesoderm lineage by hlh-8p::CRE expression. LoxN sites in the endogenous swsn-8 locus facilitate inducible knockout of swsn-8. Reference: van der Vaart A, et al. Sci Adv 2020 May 20;6(21):eaay3823. PMID: 32494730
Made byAniek van der Vaart
Laboratory SV
Reference A. van der Vaart, M. Godfrey, V. Portegijs, S. van den Heuvel, Dose-dependent functions of SWI/SNF BAF in permitting and inhibiting cell proliferation in vivo. Sci. Adv. 6, eaay3823 (2020).
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