Strain Information
Name | SV1871 View On Wormbase |
---|---|
Species | C. elegans |
Genotype | swsn-4(he268 he272 [LoxN start + LoxN intron 5]) IV; heSi208 V; heSi141 X. |
Description | heSi208 [eft- 3p::LoxP::NLS(egl-13)::tagBFP2::tbb-2 UTR::LoxP::NLS(egl-13)::mCherry::tbb-2 3'UTR] V. heSi141 [hlh-8p::CRE] X. Egg laying defective. LoxN sites in the endogenous swsn-4 locus facilitate inducible knockout of swsn-4. he268 he272 homozygotes are Egl since they cannot form a functioning vulva due to swsn-4 inactivated in the mesoderm lineage by hlh-8p::CRE expression. Reference: van der Vaart A, et al. Sci Adv 2020 May 20;6(21):eaay3823. PMID: 32494730 |
Mutagen | Crispr/Cas9 |
Outcrossed | x0 |
Made by | Aniek van der Vaart |
Laboratory | SV |
Reference | A. van der Vaart, M. Godfrey, V. Portegijs, S. van den Heuvel, Dose-dependent functions of SWI/SNF BAF in permitting and inhibiting cell proliferation in vivo. Sci. Adv. 6, eaay3823 (2020). |
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