Strain Information
| Name | SRU1 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | unc-119(ed3) III; jrsls1. |
| Description | jrsls1 [cyp-13A7p::GFP + unc-119(+)]. CYP-13A7 is the homolog of human cytochrome P450 CYP3A4, which is the major inducible xenobiotic (more than 50% of the current drugs induce its expression which adversely affect the bioavailability and half-life of the drugs). |
| Mutagen | |
| Outcrossed | x0 |
| Made by | P.S. Chakrapani |
| Laboratory | SRU |
| Reference | Chakrapani PS, Kumar S and Subramaniam JR (2008) Development and evaluation of an in vivo assay in C.elegans for screening of compounds for their effect on cytochrome P450 expression. J. of Biosciences 33(2): 269-277. |
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