Strain Information

Name SRU1   View On Wormbase
Species C. elegans
Genotypeunc-119(ed3) III; jrsls1.
Descriptionjrsls1 [cyp-13A7p::GFP + unc-119(+)]. CYP-13A7 is the homolog of human cytochrome P450 CYP3A4, which is the major inducible xenobiotic (more than 50% of the current drugs induce its expression which adversely affect the bioavailability and half-life of the drugs).
Made byP.S. Chakrapani
Laboratory SRU
Reference Chakrapani PS, Kumar S and Subramaniam JR (2008) Development and evaluation of an in vivo assay in C.elegans for screening of compounds for their effect on cytochrome P450 expression. J. of Biosciences 33(2): 269-277.
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