Strain Information
| Name | SJZ42 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | foxEx3. |
| Description | foxEx3 [rgef-1p::tomm-20::Rosella]. Pick animals with red fluorescence in neurons to maintain. foxEx3 expresses neuron-specific, mitochondrial localized Rosella, a pH-sensitive fluorescent biosensor for monitoring and analyzing mitophagy. Reference: Cummins N, EMBO J. 2019 Feb 1;38(3):e99360. PMID: 30538104 |
| Mutagen | |
| Outcrossed | x0 |
| Made by | Andrea Tweedie |
| Laboratory | SJZ |
| Reference | Disease-associated tau impairs mitophagy by inhibiting Parkin translocation to mitochondria. Cummins N, Tweedie A, Zuryn S, Bertran-Gonzalez J, Götz J. EMBO J. 2019 Feb 1;38(3):e99360. |
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