Strain Information
| Name | QR189 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | vhIs12 tbc-2(tm2241) II; unc-119(ed3) III. |
| Description | vhIs12 [vha-6p::GFP::tbc-2 + Cbr-unc-119(+)] II. vhIs12 is inserted to the left of tbc-2(m2241) in LG II. GFP::TBC-2 rescues the large endosome phenotype in the intestine of tbc-2(tm2241) animals. Outside the intestine, tbc-2(tm2241) animals have large yolk platelets in the oocytes and early embryos that are not rescued. |
| Mutagen | Bombardment |
| Outcrossed | x1 |
| Made by | Laetitia Chotard |
| Laboratory | QR |
| Reference | Chotard, L., Mishra, A. K., Sylvain, M. A., Tuck, S., Lambright, D. G., & Rocheleau, C. E. (2010). TBC-2 regulates RAB-5/RAB-7-mediated endosomal trafficking in Caenorhabditis elegans. Mol Biol Cell, 21, 2285-96. doi:10.1091/mbc.E09-11-0947 |
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