Strain Information

Name MQD2798   View On Wormbase
Species C. elegans
Genotypevit-2(crg9070[vit-2::gfp]) vit-1(hq503[vit-1::mCherry]) X.
DescriptionmCherry knocked into C terminal of vit-1 by CRISPR/Cas9 in the background of parental strain BCN9071 vit-2(crg9070[vit-2::gfp]) X. This resulting double-labelled strain was crossed six times with N2 to remove potential off-target mutations. mCherry and GFP are co-localized in the intestine, body cavity, oocyte, and embryo in adult hermaphrodites. Reference: Zhai C, et al. Aging cell, 21(11), e13719. https://doi.org/10.1111/acel.13719 PMID: 36199214.
MutagenCrispr/Cas9
Outcrossedx6
Made byChao Zhai
Laboratory MQD
Reference Zhai, C., Zhang, N., Li, X. X., Chen, X., Sun, F., & Dong, M. Q. (2022). Fusion and expansion of vitellogenin vesicles during Caenorhabditis elegans intestinal senescence. Aging cell, 21(11), e13719. https://doi.org/10.1111/acel.13719
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