Strain Information
| Name | ML2937 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | nmy-2(ne3409) I; nmy-1(mc90[nmy-1::gfp]) X. |
| Description | Maintain at 15C. nmy-2(ne3409) allele induces embryonic lethality (cytokinesis defective) at 25C. nmy-1(mc90) allele induces almost complete sterility at 25C. mc90 is a CRISPR-engineered mutation in nmy-1 at the position corresponding to the allele nmy-2(ne3409) changing NMY-2 Leucine-981 to Proline, which is conserved among nonmuscle myosins. mc90 was introduced in parental strain ML2540, which carries a GFP-tag in the endogenous nmy-1 locus. Reference: Molnar K, et al. Genetics. 2024 Sep 4;228(1):iyae109. doi: 10.1093/genetics/iyae109. PMID: 39053622. |
| Mutagen | CRISPR |
| Outcrossed | x? |
| Made by | Michel Labouesse |
| Laboratory | CGC |
| Reference | Reference: Molnar K, et al. Genetics. 2024 Sep 4;228(1):iyae109. doi: 10.1093/genetics/iyae109. PMID: 39053622. |
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