Strain Information
| Name | MCJ191 View On Wormbase |
|---|---|
| Species | C elegans |
| Genotype | mir-35(cdb2 cdb78) II. |
| Description | cdb2 cdb78 is a mutation to the 3' end of the mature mir-35 creating a mutant with mir-35 seed sequence and mir-82 3’ end. This mir-35 mutant strongly impacts embryonic abundance of mir-35 but does not affect its decay at embryo to L1. Superficially wild-type. Reference: Donnelly BF, et al. (2022). Cell Reports. |
| Mutagen | CRISPR/Cas-9 |
| Outcrossed | x1 |
| Made by | Bridget Donnelly |
| Laboratory | MCJ |
| Reference | Donnelly, B.F., Yang, B., Grimme, A.L., Vieux, K.-F., Liu, C.-Y., Zhou, L., and McJunkin, K. (2022). The developmentally-timed decay of an essential microRNA family is seed sequence-dependent. BioRxiv 2021.11.19.469346. |
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