Strain Information
| Name | MCJ13 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | mir-35(cdb2 cdb6) II. |
| Description | The seed region of the mature mir-35 is replaced with random nucleotides in mir-35(cdb2 cdb6). This mutant mir-35 has little impact on embryonic mir-35 abundance but strongly inhibits its decay at embryo to L1. Superficially wild-type. Reference: Donnelly BF, et al. (2022). Cell Reports. |
| Mutagen | CRIPSR/Cas9 |
| Outcrossed | x2 |
| Made by | Katherine McJunkin |
| Laboratory | MCJ |
| Reference | Donnelly, B.F., Yang, B., Grimme, A.L., Vieux, K.-F., Liu, C.-Y., Zhou, L., and McJunkin, K. (2022). The developmentally-timed decay of an essential microRNA family is seed sequence-dependent. BioRxiv 2021.11.19.469346. |
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