Strain Information
| Name | KG4995 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | rimb-1(ce828) III. |
| Description | Superficially wild type on plates. Slight (<10%), but significant, expansion of synaptic vesicles from the synaptic region of the DA9 motor neuron into the flanking asynaptic regions. Synaptic vesicles also showed a slight but significant accumulation in rimb-1 mutant dendrites in the DA9 motor neuron (192 +/- 32% compared to wild type; N=15; P=.015). The sequence GC TAG C TAA A TGA (3 successive stop codons in different reading frames) was inserted after codon 16 of the rimb-1 gene; described in Edwards SL, et al. (manuscript in revision). "Sentryn Acts with a Subset of Active Zone Proteins in the Guided Transport and Capture of Synaptic Vesicles in Caenorhabditis elegans." |
| Mutagen | Crispr/Cas9 |
| Outcrossed | x0 |
| Made by | Stacey Edwards |
| Laboratory | KG |
| Reference | We inserted the sequence GC TAG C TAA A TGA (3 successive stop codons in different reading frames) after codon 16 of the rimb-1 gene (out of 1276 codons total). Described in below reference: Edwards SL, Morrison LM, Manning L, Stec N, Richmond, JE, and Miller KG. (manuscruipt in revision). Sentryn Acts with a Subset of Active Zone Proteins in the Guided Transport and Capture of Synaptic Vesicles in Caenorhabditis elegans. |
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