Strain Information
| Name | KG4400 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | sad-1(ce749) X. |
| Description | Superficially wild-type on plates. Shows defects in the transport and capture of dense core vesicles and synaptic vesicles in cholinergic motor neurons. Suppresses organelle accumulation (lysosomes, early endosomes, Golgi) in axons in an unc-16(-) background. Reference: Edwards SL, et al. Genetics. 2015 Sep;201(1):91-116. Edwards SL, et al. Genetics. 2015 Sep;201(1):117-41. |
| Mutagen | EMS |
| Outcrossed | x2 |
| Made by | Ken Miller |
| Laboratory | KG |
| Reference | Edwards SL, Yorks RM, Morrison LM, Hoover CM, and Miller KG. (2015). Synapse Assembly Proteins Maintain Synaptic Vesicle Cluster Stability and Regulate Synaptic Vesicle Transport in Caenorhabditis elegans. Genetics. 201(1): 91-116. PMCID: PMC4566279. Edwards SL, Morrison LM, Yorks RM, Hoover CM, Boominathan S, and Miller KG. (2015). UNC-16 (JIP3) Acts through Synapse Assembly Proteins to Inhibit the Active Transport of Cell Soma Organelles to Caenorhabditis elegans Motor Neuron Axons. Genetic |
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