Strain Information

Name KG2430   View On Wormbase
Species C. elegans
GenotypeceIs56 X.
DescriptionceIs56 [unc-129p::ctns-1::mCherry + nlp-21p::Venus + ttx-3p::RFP]; Maps to X: 9.0 +/ 3.0 m.u. Expresses the lysosomal membrane marker CTNS-1 in a subset of 9 DA/DB cholinergic motor neurons in the ventral cord, and NLP-21::Venus in the same neurons as a marker for soluble DCV cargo and to help identify the boundaries of the somas and axons when imaging lysosomes. Reference: Edwards SL, et al. Genetics. 2015 Sep;201(1):91-116. Edwards SL, et al. Genetics. 2015 Sep;201(1):117-41.
MutagenGamma Rays
Outcrossedx2
Made byNicole Charlie
Laboratory KG
Reference Edwards SL, Yu S, Hoover, CM, Phillips BC, Richmond JE, and Miller KG. (2013). An Organelle Gatekeeper Function for Caenorhabditis elegans UNC-16 (JIP3) at the Axon Initial Segment. Genetics. 194(1): 143-161.* PMCID: PMC3632462. Edwards SL, Morrison LM, Yorks RM, Hoover CM, Boominathan S, and Miller KG. (2015). UNC-16 (JIP3) Acts through Synapse Assembly Proteins to Inhibit the Active Transport of Cell Soma Organelles to Caenorhabditis elegans Motor Neuron Axons. Genetics. 201(1): 117-141. PM
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