Strain Information

Name JRB1   View On Wormbase
Species Halicephalobus mephisto
GenotypeHalicephalobus mephisto wild isolate.
DescriptionHalicephalobus mephisto wild isolate. Grow at 37C: can survive higher temperatures than C. elegans. Useful model organism for studying heat tolerance; has expanded Hsp70 and AIG1 gene families. Has approximately 1.15% snp heterozygosity. Parthenogenetic reproduction so it cannot be out-crossed. References: Borgonie G, et al. Nature. 2011 Jun 2;474(7349):79-82. Weinstein DJ, et al. Nat Commun. 2019 Nov 21;10(1):5268.
Made byJohn Bracht
Laboratory JRB
Reference First report of organism: Borgonie, G., García-Moyano, A., Litthauer, D. et al. Nematoda from the terrestrial deep subsurface of South Africa. Nature 474, 79–82 (2011) doi:10.1038/nature09974 Full genome from Bracht lab: Weinstein, D.J., Allen, S.E., Lau, M.C.Y. et al. The genome of a subterrestrial nematode reveals adaptations to heat. Nat Commun 10, 5268 (2019) doi:10.1038/s41467-019-13245-8
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