Strain Information
| Name | JPS809 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | vxSi808 X; vxIs591. |
| Description | vxSi808 [rab-3p::APP::mCherry::unc-54 3'UTR] X. vxIs591 [tph-1p::GFP::unc-54 3'UTR]. Single-copy insertion of human APP transgene tagged with mCherry expressed throughout the nervous system, visible along ventral nerve cord, head, tail, and other neurons. GFP expression in all serotonergic neurons. References: Yi B, et al. 2017 J Neurochem 140(4): 561-575. PMID: 27926996. Mondal et al. 2018 ACS Chem Neurosci. DOI: 10.1021/acschemneuro.7b00428 PMID: 29426225 |
| Mutagen | MosSCI |
| Outcrossed | x1 |
| Made by | Wisath Sae-Lee |
| Laboratory | JPS |
| Reference | Yi et al. (2017) Small molecule modulator of sigma 2 receptor is neuroprotective and reduces cognitive deficits and neuro-inflammation in experimental models of Alzheimer |
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