Strain Information
| Name | JLF24 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | gip-1(wow5[ZF1::GFP::gip-1]) zif-1(gk117) III. |
| Description | ZF1-degron and GFP tags inserted into endogenous gip-1 locus. No overt phenotypes in a zif-1(gk117) background. Predicted no degradation because zif-1 putative null is present. Can be used for degradation of gip-1 protein by providing a source of ZIF-1. GFP fluorescence is observed at microtubule-organizing centers. Presence of ZF1-degron targets tagged proteins for ZIF-mediated degradation. Expression of ZIF-1 causes the tagged GIP-1 protein to be degraded. Reference: Sallee M, et al. PLoS Biol. 2018 Aug 6;16(8):e2005189. doi: 10.1371/journal.pbio.2005189. PMID: 30080857. |
| Mutagen | N/A |
| Outcrossed | x0 |
| Made by | Jessica Feldman |
| Laboratory | JLF |
| Reference | Sallee et al., PLoS Biol 2018 |
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