Strain Information
Name | JLF145 View On Wormbase |
---|---|
Species | C. elegans |
Genotype | zif-1(gk117) III; air-1(wow14[AIR-1::ZF::GFP::3xFLAG]) V. |
Description | ZF-degron, GFP, and 3xFLAG tags inserted into endogenous air-1 locus. No overt phenotypes in a zif-1(gk117) background. GFP expression is observed in mitotic cells at the spindle poles and along microtubules. Presence of ZF-degron targets tagged proteins for ZIF-mediated degradation. Expression of ZIF-1 causes the tagged AIR-1 protein to be degraded. Reference: Sallee M, et al. PLoS Biol. 2018 Aug 6;16(8):e2005189. doi: 10.1371/journal.pbio.2005189. PMID: 30080857. |
Mutagen | N/A |
Outcrossed | x4 |
Made by | Maria Sallee |
Laboratory | JLF |
Reference | Sallee et al., PLoS Biol 2018 |
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