Strain Information
| Name | IJ1651 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | mdt-15(yh44[mdt-15::degron::EmGFP]) III. |
| Description | Degron and EmGFP tag inserted at the 3' end of the endogenous mdt-15 gene locus by CRISPR/Cas9 engineering. This strain can be used for auxin-inducible degradation (AID) of MDT-15 protein. Reference: Lee D, et al. PLoS Biol. 2019 Aug 13;17(8):e3000415. doi: 10.1371/journal.pbio.3000415. PMID: 31408455. |
| Mutagen | No mutagen |
| Outcrossed | x4 |
| Made by | Dongyeop Lee |
| Laboratory | IJ |
| Reference | Lee D, An SWA, Jung Y, Yamaoka Y, Ryu Y, Goh GYS, Beigi A, Yang JS, Jung GY, Ma DK, Ha CM, Taubert S, Lee Y, Lee SV. MDT-15/MED15 permits longevity at low temperature via enhancing lipidostasis and proteostasis. PLoS Biol. 2019 Aug 13;17(8):e3000415. doi: 10.1371/journal.pbio.3000415. PMID: 31408455; PMCID: PMC6692015. |
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