Strain Information

Name HCL67   View On Wormbase
Species C. elegans
Genotypeunc-119(ed3) III; uocIs1.
DescriptionuocIs1 [eft-3p::Cas9(dpiRNA)::tbb-2 3' UTR + unc-119(+)]. Cas9 is optimized to remove all piRNA sites. Cas9 is expressed in the germline. Reference: Zhang D, et al. Science. 2018 Feb 2;359(6375):587-592.
MutagenNo mutagen
Outcrossedx0
Made byDonglei Zhang
Laboratory 5093
Reference The piRNA targeting rules and the resistance to piRNA silencing in endogenous genes. Donglei Zhang, Shikui Tu, Michael Stubna, Wei-Sheng Wu, Wei-Che Huang, Zhiping Weng, Heng-Chi Lee. Science02 Feb 2018 : 587-592
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