Strain Information
| Name | FJ1519 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | cdk-5(gm336) III. |
| Description | cdk-5(gm336) mutants exhibit defects in polarized trafficking of dense-core vesicles in motor neurons, and decreased localization of GLR-1::GFP to puncta in ventral nerve cord interneurons. Note that this strain does not contain GLR-1::GFP. References: Juo P, et al. Mol Biol Cell. 2007 Oct;18(10):3883-93. Goodwin PR, et al. J Neurosci. 2012 Jun 13;32(24):8158-72. |
| Mutagen | No mutagen |
| Outcrossed | x6 |
| Made by | Gian Garriga |
| Laboratory | FJ |
| Reference | Juo, P., Harbaugh, T., Garriga, G., and Kaplan, J.M. (2007).CDK-5 regulates the abundance of GLR-1 glutamate receptors in the ventral cord of Caenorhabditis elegans. Mol Biol Cell. 18:3883-3893. Goodwin, P.R., Sasaki, J.M., and Juo, P. (2012). Cyclin-dependent kinase 5 regulates polarized trafficking of neuropeptide-containing dense-core vesicles in Caenorhabditis elegans motor neurons. J Neurosci. 32:8158-8172. |
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