Strain Information

Name ESC360   View On Wormbase
Species C. elegans
Genotyperpoa-2(cse319[degron::GFP::rpoa-2]) I; emcSi71 IV.
DescriptionemcSi71 [myo-3p::TIR1::mRuby] (IV: -0.05). Maintain at 15-20C. Degron and GFP tag inserted at the N-terminus of the endogenous rpoa-2 locus. This strain can be used for auxin-inducible degradation (AID) of RPOA-2 in muscles. Reference: Zhao Q, et al. PLoS Biol. 2023 Aug 31;21(8):e3002276. doi: 10.1371/journal.pbio.3002276. PMID: 37651423.
MutagenCrispr/Cas9
Outcrossedx2
Made byQiuxia Zhao
Laboratory ESC
Reference Zhao, Q., Rangan, R., Weng, S., Ozdemir, C. , Cenik, E. S. Inhibition of ribosome biogenesis in the epidermis is sufficient to trigger organism-wide growth quiescence independently of nutritional status in C. elegans (2023). PLOS Biology, https://doi.org/10.1371/journal.pbio.3002276
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