Strain Information
| Name | ERT781 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | drh-1(jy110) IV. |
| Description | jy110 is a CRISPR-engineered deletion removing the entire drh-1 coding sequence. Susceptible to viral infection. Defective in inducing the intracellular pathogen response upon viral infection. Reference: Sowa JN, et al. J Virol. 2020 Jan 6;94(2):e01173-19. doi: 10.1128/JVI.01173-19. PMID: 31619561. |
| Mutagen | CRIPSR/Cas9, microinjection |
| Outcrossed | x3 |
| Made by | Jessica Sowa |
| Laboratory | ERT |
| Reference | Sowa JN, Jiang H, Somasundaram L, Tecle E, Xu G, Wang D, Troemel ER. The Caenorhabditis elegans RIG-I Homolog DRH-1 Mediates the Intracellular Pathogen Response upon Viral Infection. J Virol. 2020 Jan 6;94(2):e01173-19. doi: 10.1128/JVI.01173-19. PMID: 31619561; PMCID: PMC6955277. |
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