Strain Information
| Name | ERS100 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | eraIs1. |
| Description | eraIs1 [dat-1p::mCherry + dat-1p::hSNCA::Venus]. Inclusions of human alpha-Synuclein::Venus in dopaminergic neurons with marked with mCherry. Overexpression of human SNCA (alpha-Synuclein tagged with Venus) causes degenerative signs in dopaminergic neurons. Reference: Vozdek R, et al. 2022 Apr 27:14:806000. doi: 10.3389/fnagi.2022.806000. PMID: 35572147. |
| Mutagen | integrated by UV |
| Outcrossed | x5 |
| Made by | Roman Vozdek |
| Laboratory | 5704 |
| Reference | https://www.frontiersin.org/articles/10.3389/fnagi.2022.806000/full |
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