Strain Information
| Name | ERC84 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | top-1(ers56[top-1::degron::GFP]) I; ieSi57 II. |
| Description | ieSi57 [eft-3p::TIR1::mRuby::unc-54 3'UTR + Cbr-unc-119(+)] II. Degron tag inserted at the end of exon five in the endogenous top-1 locus. ieSi57 is a single-copy transgene insertion into chromosome II (oxTi179) expressing modified Arabidopsis thaliana TIR1 tagged with mRuby in the soma. This strain can be used for auxin-inducible degradation (AID) of target proteins in somatic tissues. Reference: Morao AK, et al. Mol Cell. 2022 Nov 17;82(22):4202-4217.e5. doi: 10.1016/j.molcel.2022.10.002. PMID: 36302374. |
| Mutagen | |
| Outcrossed | x0 |
| Made by | Ana Morao |
| Laboratory | ERC |
| Reference | PMID: 36302374 DOI: 10.1016/j.molcel.2022.10.002 |
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