Strain Information
Name | ERC82 View On Wormbase |
---|---|
Species | C. elegans |
Genotype | ieSi57 II; ers54[dpy-27::degron::GFP] III. |
Description | ieSi57 [eft-3p::TIR1::mRuby::unc-54 3'UTR + Cbr-unc-119(+)] II. Degron::GFP tag inserted into the endogenous dpy-27 locus. Dumpy, Him, X chromosome dosage compensation hypomorph. ieSi57 is a single-copy transgene insertion into chromosome II (oxTi179) expressing modified Arabidopsis thaliana TIR1 tagged with mRuby in the soma. This strain can be used for auxin-inducible degradation (AID) of target proteins in somatic tissues. Reference: Morao AK, et al. Mol Cell. 2022 Nov 17;82(22):4202-4217.e5. doi: 10.1016/j.molcel.2022.10.002. PMID: 36302374. |
Mutagen | No mutagen |
Outcrossed | x0 |
Made by | Ana Morao |
Laboratory | ERC |
Reference | PMID: 36302374 DOI: 10.1016/j.molcel.2022.10.002 |
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