Strain Information
| Name | DQM1041 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | bmdSi282. |
| Description | bmdSi282 [^loxN^rgef-1p::mKate2-STOP-STOP-VHH4GFP::DAMc1]. Wild-type growth and movement. NanoDam toolkit will allows identification of direct genomic targets of TFs as well as chromatin modifiers. In this system, Dam methylase is fused with a binding reagent, an anti-GFP nanobody (vhhGFP4). Thus, genome-wide profiling can be achieved by combining cell type-specific Dam::vhhGFP4 fusion constructs with GFP knock-in alleles. |
| Mutagen | No mutagen |
| Outcrossed | x2 |
| Made by | Taylor N. Medwig-Kinney |
| Laboratory | DQM |
| Reference | We are going to have a pre-print describing a new DamID-based approach, called NanoDam-ID in C. elegans, for genome-wide profiling targets, collaborating with Dr. Callista Yee and Dr. Michalis Barkoulas. Mechanisms of this tool is described below (other reason). |
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