Strain Information

Name COP1879   View On Wormbase
Species C. elegans
Genotypeunc-68(knu765) V.
DescriptionThe UNC-68a G350R missense mutation (knu765) corresponds to a human myopathic variant, RyR1:p.G341R. Subtle effects on locomotion, and altered response to halothane and aldicarb. Reference: Graham B, et al. Front. Genet. 2020; 11:37. doi: 10.3389/fgene.2020.00037 PMID: 32174957
MutagenNo mutagen
Outcrossedx0
Made byBrittany Graham
Laboratory UL
Reference Graham B, Shaw M-A and Hope IA (2020) Single Amino Acid Changes in the Ryanodine Receptor in the Human Population Have Effects In Vivo on Caenorhabditis elegans Neuro- Muscular Function. Front. Genet. 11:37. doi: 10.3389/fgene.2020.00037
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