Strain Information

Name CLP546   View On Wormbase
Species C. elegans
GenotypetwnEx185.
DescriptiontwnEx185 [mec-7p::MTS::roGFP + mec-7p::TOMM20::mCherry + ttx-3p::GFP]. Pick animals with GFP expression in head neurons (AIY) to maintain. roGFP can be used to monitor redox status of the mitochondrial matrix in the six touch receptor neurons: the oxidation-reduction status of mitochondrial matrix can be monitored with roGFP, a GFP variant that increases brightness in a more oxidized environment. The mitochondrial outer membrane in these neurons are marked by mCherry. Reference: Jiang HC, et al. Proc Natl Acad Sci USA. 2015 Jul 14;112(28):8768-73. doi: 10.1073/pnas.1501831112. PMID: 26124107. [NOTE: twnEx185 is incorrectly described as carrying myo-2p::GFP in the reference publication. The correct co-injection marker is ttx-3::GFP.]
MutagenNo mutagen
Outcrossedx0
Made byHao-Ching Jiang
Laboratory CLP
Reference Jiang et al., PNAS 2015; 112(28): 8768-8773. Note: the "Pmyo-2::GFP" part of the genotype of twnEx185 in the reference should be corrected as "Pttx-3::GFP".
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