Strain Information

Name CLP1445   View On Wormbase
Species C. elegans
Genotypepmp-4(twn16) IV; twnEx656.
DescriptiontwnEx656 [pmp-4p::pmp-4 + elt-2p::GFP]. Pick GFP+ animals to maintain. Superficially wild-type. twnEx656 contains 1.2 kb pmp-4 promoter driving expression of 2.2 kb pmp-4 cDNA; transgene rescues behavioral phenotype of twn16 mutants. twn16 is a 1651 bp deletion removing 1027 bp of the promoter sequence, the transcriptional start site, and the first two exons of pmp-4. twn16 has been out-crossed 3 times in this strain. Reference: Tsai SH, et al. Cell Rep. 2024 Mar 22;43(4):113996. doi: 10.1016/j.celrep.2024.113996. PMID: 38520690.
MutagenNo mutagen
Outcrossedx3
Made byShang-Heng Tsai
Laboratory CLP
Reference Tsai SH, Wu YC, Palomino DF, Schroeder FC, Pan CL. Peripheral Peroxisomal β-Oxidation Engages Neuronal Serotonin Signaling to Drive Stress-Induced Aversive Memory in C. elegans. Cell Reports 2024; 43: 113996.
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