Strain Information
Name | CL2355 View On Wormbase |
---|---|
Species | C. elegans |
Genotype | smg-1(cc546) dvIs50 I. |
Description | dvIs50 [pCL45 (snb-1::Abeta 1-42::3' UTR(long) + mtl-2::GFP] I. Maintain at 16C. Pan-neuronal expresion of human Abeta peptide. Constitutive intestinal expression of GFP from marker transgene. Strain shows deficits in chemotaxis, associative learning, and thrashing in liquid. Strain also has incomplete sterility due to germline proliferation defects and embryonic lethality. Maintain at 16 C to reduce selection against transgene, although this does not alter the partial sterility. Reference: Wu Y., et al. J Neurosci. 2006 Dec 13;26(50):13102-13. |
Mutagen | gamma irradiation |
Outcrossed | x3 |
Made by | Chris Link |
Laboratory | CL |
Sign in
or
register an account if you want to order this strain.