Strain Information
| Name | BN1024 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | emr-1(bq34[emr-1::mCherry]) I. |
| Description | mCherry tag inserted at C-terminus of endogenous emr-1 locus using CRISPR/Cas9 contains FRT sites in 1st intron of emr-1 and 1st intron of mCherry to enable FLP-mediated conditional gene knockout. Reference: Romero-Bueno R, et al. EMBO J. 43(22): 5718-5746. doi: 10.1038/s44318-024-00261-8. PMID: 39367234. |
| Mutagen | No mutagen |
| Outcrossed | x2 |
| Made by | Cristina Ayuso |
| Laboratory | BN |
| Reference | Romero-Bueno R, Fragoso-Luna A, Ayuso C, Mellmann N, Kavsek A, Riedel CG, Ward JD, Askjaer P. 2024. A human progeria-associated BAF-1 mutation modulates gene expression and accelerates aging in C. elegans. EMBO J. 43(22): 5718-5746. doi: 10.1038/s44318-024-00261-8. |
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