Strain Information
| Name | BAY7 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | yanSi1 II; unc-119(ed3) III. |
| Description | yanSi1 [eft-3p::dCAS9::VP64::tbb-2 3'UTR + Cbr-unc-119(+)] inserted into ttTi5605 (II:8.42 MB) in parental strain EG6699. Integration plasmid was generated via 3-way gateway reaction with pCFJ150 and plasmids containing eft-3 promoter (ID:1031@E02 promoterome), tbb-2 3'UTR (pCM1.36), and a full length dcas9::VP64 transgene cloned into pDONR201. Reference: Zullo JM, et al. Nature. 2019 Oct;574(7778):359-364. doi: 10.1038/s41586-019-1647-8. PMID: 31619788. |
| Mutagen | No mutagen |
| Outcrossed | x0 |
| Made by | Joe Zullo |
| Laboratory | BAY |
| Reference | Regulation of lifespan by neural excitation and REST https://pubmed.ncbi.nlm.nih.gov/31619788/ |
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