Strain Information

Name AV477   View On Wormbase
Species C. elegans
Genotypedsb-2(me96) II.
DescriptionAge-dependent defect in meiotic double-strand break formation. Homozygous mutants produce elevated frequency of males and dead embryos resulting from defects in meiotic chromosome segregation. The frequency of both males and dead embryos increases in later broods. Reference: Rosu S, et al. PLoS Genet. 2013;9(8):e1003674.
MutagenEMS
Outcrossedx4
Made bySimona Rosu
Laboratory AV
Reference Rosu S, Zawadzki KA, Stamper EL, et al. The C. elegans DSB-2 Protein Reveals a Regulatory Network that Controls Competence for Meiotic DSB Formation and Promotes Crossover Assurance. Sekelsky J, ed. PLoS Genetics. 2013;9(8):e1003674. doi:10.1371/journal.pgen.1003674.
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