Strain Information
| Name | AUM2059 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | vizSi20 II; unc-119(ed3) III. |
| Description | vizSi20 [mex-5p::GFP::gsk-3 (K65A,E77A,D161A,D180A)::tbb-2 3’UTR + unc-119(+)] II. Superficially wild-type. vizSi20 was inserted into Chr II ttTi5605 using MosSci. GSK-3 cDNA was rendered kinase dead by replacing K65, E77, D161 and D180 to alanine. The transgene does not rescue gsk-3 sterility or embryonic lethality defects. Reference: Furuta T, et al. Development. 2018 May 14;145(10). pii: dev161042. doi: 10.1242/dev.161042. |
| Mutagen | No mutagen |
| Outcrossed | x3x |
| Made by | Tokyo Furuta |
| Laboratory | AUM |
| Reference | GSK-3 promotes S-phase entry and progression in C. elegans germline stem cells to maintain tissue output. Development. 2018 May 14;145(10). pii: dev161042. doi: 10.1242/dev.161042. Furuta T, Joo HJ, Trimmer KA, Chen SY, Arur S |
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