Strain Information
| Name | APL130 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | ljfSi10 II; egl-17(ljf25[egl-17::mNG::nlg-1 C-terminus]) X. |
| Description | ljfSi10 [hlh-8p::2x mTurquoise2::PH::tbb-2 3'UTR loxN] II. Endogenously membrane tethered allele of EGL-17::mNG that is competent for contact-dependent signaling but does not diffuse extracellularly. egl-17(ljf25) was generated by inserting mNG and the transmembrane and C-terminal domains of NLG-1 at the C-terminus of egl-17. Sex myoblast migration defects, Egl. mTurquoise2::PH plasma membrane marker that is expressed in the M lineage. ljfSi10 was inserted at Chr II:8420157-8420243, near ttTi5605, using Cas9-triggered homologous recombination. Reference: Gibney TV & Pani AM. Development. 2025 Aug 21:dev.204802. doi: 10.1242/dev.204802. PMID: 40838367. |
| Mutagen | Crispr/Cas9 |
| Outcrossed | x0 |
| Made by | Theresa Gibney |
| Laboratory | APL |
| Reference | Gibney TV, Pani AM. FGF diffusion is required for directed migration of postembryonic muscle progenitors in C. elegans. Development. 2025 Aug 21:dev.204802. doi: 10.1242/dev.204802. PMID: 40838367. |
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