Strain Information

Name AML320   View On Wormbase
Species C. elegans
GenotypeotIs669 V; wtfIs145.
DescriptionwtfIs145 [rab-3p::his-24::GCaMP6s::unc-54 3' UTR + pBX]. GCaMP6s transgene allows for imaging whole-brain calcium activity with neuronal identification using NeuroPAL system. See description of strain OH15262 for full description of otIs669 NeuroPAL (Neuronal Polychromatic Atlas of Landmarks) transgene (Yemini E, et al. Cell. 2021 Jan 7;184(1):272-288.e11. PMID: 33378642). Derived by out-crossing parental strain OH15262 an additional six times before incorporating wtfIs145. References: Yu X, et al. Elife. 2021 Jul 14;10:e66410. doi: 10.7554/eLife.66410. PMID: 34259623. Randi F, et al. Nature 2023 Nov;623(7986):406-414. doi: 10.1038/s41586-023-06683-4. PMID: 37914938. Sharma AK, et al. Genetics 2024 May 11:iyae077. doi: 10.1093/genetics/iyae077 PMID: 38733622.
Mutagennone
Outcrossedx6
Made byAnuj Kumar Sharma
Laboratory AML
Reference Xinwei Yu Matthew S Creamer Francesco Randi Anuj K Sharma Scott W Linderman Andrew M Leifer (2021). Fast deep neural correspondence for tracking and identifying neurons in C. elegans using semi-synthetic training eLife 10:e66410. https://doi.org/10.7554/eLife.66410 and Francesco Randi, Anuj K. Sharma, Sophie Dvali, Andrew M. Leifer (2022). A functional connectivity atlas of C. elegans measured by neural activation. arXiv:2208.04790. https://doi.org/10.48550/arXiv.2208.04790
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