Laboratory Information
| Name | TWH View on WormBase |
|---|---|
| Allele designation | yyz |
| Head | Kalia, Lorraine |
| Institution | Toronto Western Hospital, Toronto, ON, Canada |
| Address | Krembil Research Institution Rm. 8KD-408 60 Leonard Ave. Toronto M5T 2R1 Canada |
| Gene classes |
Strains contributed by this laboratory
| Strain | Genotype | Species | Description |
|---|---|---|---|
| TWH179 | hrpr-1(yyz8) I; tmIs905 II; egIs1 IV. | C.elegans | tmIs905 [dat-1p::alpha-synuclein(A30P) + ges-1p::DsRed] II. egIs1 [dat-1p::GFP]; reportedly maps to LG IV. hrpr-1 also known as hrp-2. yyz8 is a weak loss-of-function allele. Neurodegeneration in ADE neurons. Neurites are shorter in PDE neurons. |
| TWH211 | hrpr-1(yyz8) I; sid-1(pk3321) uIs69 V; egIs1. | C.elegans | uIs69 [(pCFJ90) myo-2p::mCherry + unc-119p::sid-1]. egIs1 [dat-1p::GFP]. hrpr-1 also known as hrp-2. Derived from parental strain TU3401, which has been reported as showing RNAi response in non-neuronal tissues. |
| TWH283 | hrpr-1(yyz8) I; tmIs905 II; egIs1 IV; yyzSi1. | C.elegans | tmIs905 [dat-1p::alpha-synuclein(A30P) + ges-1p::DsRed] II. egIs1 [dat-1p::GFP]; reportedly maps to LG IV. yyzSi1 [dat-1p::hrpr-1(genomic)::hrpr-1 3'UTR + HygR]. Transgene expression in dopaminergic neurons rescues yyz8 phenotype. hrpr-1 also known as hrp-2. |
| TWH334 | yyzEx41. | C.elegans | yyzEx41 [dat-1p::UbG76V::mRuby::T2A::mClover + rol-6(su1006)]. Pick Rollers to maintain. Red and green fluorescence in dopaminergic neurons. TWH336 can be used as a control strain. |
| TWH335 | sid-1(pk3321) uIs69 V; yyzEx41. | C.elegans | uIs69 [pCFJ90 (myo-2p::mCherry) + unc-119p::sid-1]. yyzEx41 [dat-1p::UbG76V::mRuby::T2A::mClover + rol-6(su1006)]. Pick Rollers to maintain. Red and green fluorescence in dopaminergic neurons. Red fluorescence in pharynx. Derived from parental strain TU3401, which has been reported as showing RNAi response in non-neuronal tissues. |
| TWH336 | yyzEx42. | C.elegans | yyzEx42 [dat-1p::mRuby::T2A::mClover + rol-6(su1006)]. Pick Rollers to maintain. Red and green fluorescence in dopaminergic neurons. Can be used as a control for Ub::mRuby in dopaminergic neurons to analyze UPS activity. |
| TWH337 | sid-1(pk3321) uIs69 V; yyzEx42. | C.elegans | uIs69 [pCFJ90 (myo-2p::mCherry) + unc-119p::sid-1]. yyzEx42 [dat-1p::mRuby::T2A::mClover + rol-6(su1006)]. Pick Rollers to maintain. Red and green fluorescence in dopaminergic neurons. Derived from parental strain TU3401, which has been reported as showing RNAi response in non-neuronal tissues. |
| TWH388 | egIs1 IV; yyzSi9. | C. elegans | egIs1 [dat-1p::GFP]; reportedly maps to LG IV. yyzSi9 [rab-3p::hrp-2(cDNA)::mRuby::hrpr-1 3'UTR + HygR]. Hygromycin resistant. hrpr-1 transgene expression in neurons. hrpr-1 also known as hrp-2. |
This laboratory hasn't submitted any alleles to the CGC.