Laboratory Information

NameSBP View on WormBase
Allele designationmgw
HeadPierce, Sarah
InstitutionUniversity of Washington, Seattle, WA
Address 1959 NE Pacific St
HSB/K160
Box 357720
Seattle 98115-7720
United States
Website http://www.gs.washington.edu/faculty/king.htm
Gene classes

Strains contributed by this laboratory

Strain Genotype Species Description
SBP67 spat-3(mgw14[R209Q]) X. C. elegans Egl, with defects in HSN migration, and HSN and PVQ axon guidance. Crispr/Cas9 induced mutation in Ring1 domain with epigenetic effects on neurodevelopment. Amino acid substitution that likely disrupts interaction with a specific substrate, resulting in a phenotype comparable to a complete gene deletion. Reference: Pierce SB, et al. Proc Natl Acad Sci U S A. 2018 Feb 13;115(7):1558-1563.
SBP74 spat-3(mgw26) X. C. elegans Egl, with defects in HSN migration, and HSN and PVQ axon guidance. Crispr/Cas9 induced deletion. Reference: Pierce SB, et al. Proc Natl Acad Sci U S A. 2018 Feb 13;115(7):1558-1563.
This laboratory hasn't submitted any alleles to the CGC.