Laboratory Information
Name | SBP View on WormBase |
---|---|
Allele designation | mgw |
Head | Pierce, Sarah |
Institution | University of Washington, Seattle, WA |
Address | 1959 NE Pacific St HSB/K160 Box 357720 Seattle 98115-7720 United States |
Website | http://www.gs.washington.edu/faculty/king.htm |
Gene classes |
Strains contributed by this laboratory
Strain | Genotype | Species | Description |
---|---|---|---|
SBP67 | spat-3(mgw14[R209Q]) X. | C. elegans | Egl, with defects in HSN migration, and HSN and PVQ axon guidance. Crispr/Cas9 induced mutation in Ring1 domain with epigenetic effects on neurodevelopment. Amino acid substitution that likely disrupts interaction with a specific substrate, resulting in a phenotype comparable to a complete gene deletion. Reference: Pierce SB, et al. Proc Natl Acad Sci U S A. 2018 Feb 13;115(7):1558-1563. |
SBP74 | spat-3(mgw26) X. | C. elegans | Egl, with defects in HSN migration, and HSN and PVQ axon guidance. Crispr/Cas9 induced deletion. Reference: Pierce SB, et al. Proc Natl Acad Sci U S A. 2018 Feb 13;115(7):1558-1563. |
This laboratory hasn't submitted any alleles to the CGC.