Laboratory Information
| Name | MAS View on WormBase |
|---|---|
| Allele designation | abc |
| Head | Martin Srayko |
| Institution | University of Alberta, Edmonton, Canada |
| Address | CW405, Biological Sciences Building University of Alberta Edmonton T6G2E9 Canada |
| Website | https://www.ualberta.ca/science/about-us/contact-us/faculty-directory/martin-srayko |
| Gene classes | memi |
Strains contributed by this laboratory
| Strain | Genotype | Species | Description |
|---|---|---|---|
| MAS37 | unc-119(ed3) III; abcIs3. | C. elegans | abcIs3 [pie-1p::ebp-2::GFP + unc-119(+)]. Superficially wild-type. Maternal expression of EBP-2::GFP microtubule end-binding protein. In early embryos, EBP-2 encodes an EB1-like protein (end-binding) that locates to the growing tips of microtubules (not detected on depolymerizing microtubules). A strong fluorescent signal localizes to the centrosome due to high concentration of polymerizing microtubule ends. References: Gusnowski EM, Srayko M. J Cell Biol. 2011 Aug 8;194(3):377-86. Tegha-Dunghu J, et al. Methods Mol Biol. 2014;1136:103-16. |
| MAS94 | mei-1(ct46) unc-13(e1091) I; unc-119(ed3) III; abcIs3. | C. elegans | abcIs3 [pie-1p::ebp-2::GFP + unc-119(+)]. Embryonic-lethal at 25ºC due to dominant gain-of-function mutation mei-1(ct46), and Uncoordinated due to unc-13 mutation. Maternal expression of EBP-2::GFP microtubule end-binding protein. EBP-2 encodes an EB1-like protein (end-binding) that, in early embryos, locates to the growing tips of microtubules. A strong fluorescent signal localizes to the centrosomes of early embryos due to a high concentration of polymerizing microtubules. mei-1(ct46)-based ectopic microtubule severing causes mitotic spindle defects in the early embryo. References: Gusnowski EM, Srayko M. J Cell Biol. 2011 Aug 8;194(3):377-86. Tegha-Dunghu J, et al. Methods Mol Biol. 2014;1136:103-16. |
This laboratory hasn't submitted any alleles to the CGC.