Laboratory Information
| Name | 5151 View on WormBase |
|---|---|
| Allele designation | |
| Head | Zhang, Huimin |
| Institution | IBMS, Soochow University, SuZhou, China |
| Address | 199 Ren-Ai Road Building 703 Room 3406 IBMS, Soochow University Suzhou 215123 China |
| Website | http://ibms.suda.edu.cn/3479/list.htm |
| Gene classes |
Strains contributed by this laboratory
| Strain | Genotype | Species | Description |
|---|---|---|---|
| HMZ245 | ccar-1(sda11) IV. | C. elegans | Superficially wild-type except for a slightly shorter body length in adults. Crispr/Cas9 was used to create a 13 bp deletion in exon7 of ccar-1a; breakpoints: CTGATTCGGGAG/sda11/ATCGGAAGTTTC. sda11 is an isoform-specific deletion allele. It only affects the function of CCAR-1A and CCAR-1D, but not CCAR-1B and C. In addition, because CCAR-1D is not expressed in embryos,this allele can be used to specifically inactivate CCAR-1A (the full-length isoform that is the most similar to human CCAR1) during embryogenesis. Reference: Fu R, et al. J Cell Sci. 2018 May 10. |
This laboratory hasn't submitted any alleles to the CGC.