| PT8 |
C. elegans |
pkd-2(sy606) IV; him-5(e1490) V. Show Description
Males are response and location-of-vulva defective. pkd-2(sy606) is a 2396 bp deletion (8388 to 5942 in YAC Y73F8A); mutant protein is predicted to contain the N-terminal portion of the protein midway through the first predicted transmembrane region.
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| PS3398 |
C. elegans |
lov-1(sy582) II; pkd-2(sy606) IV; him-5(e1490) V. Show Description
Double mutant phenotype resembles that of the single mutants. Do not distribute this strain; other labs should request it from the CGC.
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| EM886 |
C. elegans |
rax-2(bx131) III; bxIs14 him-5(e1490) V. Show Description
bxIs14 [pkd-2::GFP + pdx-1]. Ray axon defective.
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| EM902 |
C. elegans |
madd-2(bx132) bxIs14 him-5(e1490) V. Show Description
bxIs14 [pkd-2::GFP + pdx-1]. Ray axon defective.
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| EM905 |
C. elegans |
rax-5(bs137) II; bxIs14 him-5(e1490) V. Show Description
bxIs14 [pkd-2::GFP + pdx-1]. Ray axon defective.
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| EM907 |
C. elegans |
rax-3(bx133) I; bxIs14 him-5(e1490) V. Show Description
bxIs14 [pkd-2::GFP + pdx-1]. Ray axon defective.
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| EM908 |
C. elegans |
rax-3(bx138) I; bxIs14 him-5(e1490) V. Show Description
bxIs14 [pkd-2::GFP + pdx-1]. Ray axon defective.
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| EM909 |
C. elegans |
rax-4(bx139) I; bxIs14 him-5(e1490) V. Show Description
bxIs14 [pkd-2::GFP + pdx-1]. Ray axon defective.
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| EM911 |
C. elegans |
rax-6(bx140) IV; bxIs14 him-5(e1490) V. Show Description
bxIs14 [pkd-2::GFP + pdx-1]. Ray axon defective.
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| MT11318 |
C. elegans |
nIs133 I; ceh-30(n3714) X. Show Description
nIs133 [pkd-2::GFP]. Reference: Schwartz HT & Horvitz HR (2007) Genes Dev 21(23):3181-94.
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| PT1443 |
C. elegans |
inpp-5K(my15) III; him-5(e1490) V. Show Description
Spermatogenesis abnormal with small brood size. PKD-2::GFP ciliary localization defective. Maintain at 20 C. inpp-5K formerly known as cil-1. Reference: Bae Y, et al. 2009 Curr Bio 19(19):1599-607.
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| PT3562 |
C. elegans |
sid-2(my95[sid-2::mScarlet]) III; him-5 (e1490) V; myIs4. Show Description
myIs4 [pkd-2p::pkd-2::GFP + unc-122p::GFP]. Phenotypically normal. sid-2::mScarlet is functional in environmental RNAi. Reference: Nikonorova IA, et al. Curr Biol. 2022 Mar 19;S0960-9822(22)00396-7. PMID: 35334227
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| PT442 |
C. elegans |
klp-6(sy511) III; him-5(e1490) V. Show Description
Males Lov and response defective. Mislocalizes pkd-2::GFP in cilia. sy511 contains a nonsense mutation in exon 10 (C-T transition = Q706stop).
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