Laboratory Information

NameZB View on WormBase
Allele designationbz
HeadMonica A Driscoll
InstitutionRutgers University
Address Rutgers University
Nelson Labs A220
604 Allison Road
Piscataway 08854
United States
Website http://lifesci.rutgers.edu/~molbiosci/faculty/driscoll.html
Gene classes acd  del  efk  hpa  kvs  mps  pbd 

Strains contributed by this laboratory

Strain Genotype Species Description
ZB1028 crt-1(bz29) V. C. elegans Probably null calreticulin. W28 amber. Slow growth (one day developmental delay). Nearly sterile if raised at 25C. Suppresses mec-4(d)-induced neurodegeneration. Bent-head.
ZB1029 crt-1(bz30) V. C. elegans Probably null W231opa. Probably null calreticulin - slow growth (one day developmental delay). Nearly sterile if reared at 25C. Suppresses mec-4(d)-induced neurodegeneration. Bent-head.
ZB1030 crt-1(bz31) V. C. elegans Point mutation C133Y. No easily detected phenotype, selected for suppression of mec-4(d)-induced degeneration caused by ectopic expression of mec-4(d)-induced neurodegeneration. Bent-head.
ZB1031 crt-1(bz50) V. C. elegans Point mutation in G102E. No easily detected phenotype, selected for suppression of mec-4(d)-induced degeneration caused by ectopic expression of mec-4(u231) in the ventral nerve cord. Bent-head.
ZB1057 bzIs18. C. elegans bzIs18 [mec-4p::Yc2.12 + lin-15(+)].
ZB1098 glt-4(bz69) II. C. elegans Reference: Mano et al. (2007) J Biol Chem 282(47):34412-9.
ZB1099 glt-5(bz70) II. C. elegans Reference: Mano et al. (2007) J Biol Chem 282(47):34412-9.
ZB1102 glt-3(bz34) IV; nuIs5 V. C. elegans nuIs5 [glr-1::GFP + glr-1::G(alpha)s(Q227L) V + lin-15(+)] V. Reference: Mano & Driscoll (2009) J Neurochem 108(6):1373-84.
ZB1106 glt-3(bz34) IV; glt-1(ok206) X. C. elegans Reference: Mano et al. (2007) J Biol Chem 282(47):34412-9.
ZB1108 bzEx?. C. elegans bzEx? [glt-3::GFP + rol-6(su1006)]. Rollers. Maintain by picking rollers. Reference: Mano et al. (2007) J Biol Chem 282(47):34412-9.
ZB1110 bzEx?. C. elegans bzEx? [glt-4::GFP + rol-6(su1006)]. Rollers. Maintain by picking rollers. Reference: Mano et al. (2007) J Biol Chem 282(47):34412-9.
ZB2551 mec-10(tm1552) X. C. elegans
ZB2844 hpa-1(tm3256) IV. C. elegans Reference: Iwasa H, et al. Aging Cell. 2010 Aug;9(4):490-505.
ZB2845 hpa-2(tm3827) II. C. elegans Reference: Iwasa H, et al. Aging Cell. 2010 Aug;9(4):490-505.
ZB547 ced-12(bz187) I. C. elegans Induces persistence of programmed cell death corpses and necrotic cell death corpses.

Alleles contributed by this laboratory

Allele Type DNA Change Protein Change
bz34 Allele deletion
bz29 Allele substitution nonsense
bz30 Allele substitution nonsense
bz31 Allele substitution
bz50 Allele substitution
bz69 Allele deletion
bz70 Allele deletion
bz187 Allele substitution nonsense