Laboratory Information
Name | YE View on WormBase |
Allele designation | zm |
Head | Chan, Ray |
Institution | University of Michigan, Ann Arbor, MI |
Address |
Human Genetics & Internal Medicine
University of Michigan Medical School
4909 Buhl Bldg.
1241 E. Catherine Street
Ann Arbor, MI 48109-0618 |
Gene classes |
|
Strains contributed by this laboratory
Strain |
Genotype |
Species |
Description |
YE57 |
smc-5(ok2421)/mIn1 [mIs14 dpy-10(e128)] II. |
C. elegans |
Homozygous viable mutation balanced by GFP- and dpy-10-marked inversion. Heterozygotes are WT with relatively dim pharyngeal GFP signal, and segregate WT dim GFP, Dpy bright GFP (mIn1 homozygotes), and non-GFP ok2421 homozygotes. Pick WT dim GFP and check for correct segregation of progeny to maintain. ok2421 homozygotes are morphologically wild-type but show ~30% reduction in fertilized eggs and a trans-generational increase in sterility. Maintain under normal conditions. Reference: Bickel JS, et al. PLoS Genet. 2010 Jul 22;6(7):e1001028. |
YE58 |
smc-6(ok3294)/mIn1 [mIs14 dpy-10(e128)] II. |
C. elegans |
Homozygous viable mutation balanced by GFP- and dpy-10-marked inversion. Heterozygotes are WT with relatively dim pharyngeal GFP signal, and segregate WT dim GFP, Dpy bright GFP (mIn1 homozygotes), and non-GFP ok3294 homozygotes. Pick WT dim GFP and check for correct segregation of progeny to maintain. ok3294 homozygotes are morphologically wild-type but show ~30% reduction in fertilized eggs and a trans-generational increase in sterility. Maintain under normal conditions. Reference: Bickel JS, et al. PLoS Genet. 2010 Jul 22;6(7):e1001028. |
YE59 |
smc-5(tm2868)/mIn1 [mIs14 dpy-10(e128)] II. |
C. elegans |
Homozygous viable mutation balanced by GFP- and dpy-10-marked inversion. Heterozygotes are WT with relatively dim pharyngeal GFP signal, and segregate WT dim GFP, Dpy bright GFP (mIn1 homozygotes), and non-GFP tm2868 homozygotes. Pick WT dim GFP and check for correct segregation of progeny to maintain. tm2868 homozygotes are morphologically wild-type but show ~30% reduction in fertilized eggs and a trans-generational increase in sterility. Maintain under normal conditions. Reference: Bickel JS, et al. PLoS Genet. 2010 Jul 22;6(7):e1001028. |
This laboratory hasn't submitted any alleles to the CGC.