| NF87 |
ced-12(k149) I. |
C. elegans |
Cell corpses persist as unengulfed, refractile dics. DTC mismigrates. Sequenced: point mutation R38>STOP, probably a null. |
| WS1137 |
cpb-3(op234) I. |
C. elegans |
High physiological germ-line apoptosis. op234 was originally assigned to gla-1, but cloning revealed it to be a point mutation in cpb-3 causing a C520Y substitution at an invariant cysteine within the conserved C/H domain. |
| WS1433 |
hus-1(op241) I; unc-119(ed3) III; opIs34. |
C. elegans |
opIs34 [hus-1p::hus-1::GFP + unc-119(+)]. Low-copy integrated array of 1144 bp hus-1 promoter and genomic coding sequence fused to GFP. Nuclear expression of GFP in germ cells and embryos. Integrated GFP construct completely rescues DNA damage induced cell cycle arrest defect and partially rescues DNA damage induced apoptosis of hus-1(op241). |
| WS1609 |
unc-69(ok339)/qC1 [dpy-19(e1259) glp-1(q339) III. |
C. elegans |
Heterozygotes are WT and segregate WT, Dpy Steriles and arrested L1 coilers. Fails to complement unc-50. |
| WS1642 |
rpoa-2(op259) I. |
C. elegans |
Maintain at 15-20C. Sterile at 25C. Apoptosis variant. Small germ line. |
| WS1973 |
opIs56. |
C. elegans |
opIs56 [egl-1p::2xNLS::GFP]. opIs56 is a low copy integrant of 3 kb 5' sequence from egl-1 fused to 2xNLS GFP. unc-119(ed3) should be outcrossed. Low basal GFP expression in embryos, meiotic germ cells and several neurons. GFP expression can be induced by ionizing radiation in all germ cells. Best viewed with dissected gonads. |
| WS2072 |
opIs76 I; unc-119(ed3) III. |
C. elegans |
opIs76 [cyb-1p::cyb-1::YFP + unc-119(+)]. The fusion protein partially rescues a cyb-1 null allele, so it is at least partially functional. non-Unc strain. |
| WS2170 |
unc-119(ed3) III; opIs110 IV. |
C. elegans |
opIs110 [lim-7p::YFP::actin + unc-119(+)] IV. YFP::ACT-5 expressed in somatic sheath cells, marks pre-disc corpses. |
| WS2265 |
hus-1(op244) I/hT2 [bli-4(e937) let-?(q782) qIs48] (I;III). |
C. elegans |
Heterozygotes are WT GFP+ and segregate non-glowing hus-1 homozygotes and very rare homozygous hT2 glowing animals, and dead eggs. qIs48 is an insertion of ccEx9747 with markers: myo-2::GFP expressed brightly in the pharynx throughout development, pes-10::GFP expressed in embryos, and gut promoter driving GFP in the intestine. hus-1(op244) mutants from homozygous parents show an incompletely penetrant maternal effect embryonic lethality. Note: qIs48 has been observed to recombine off hT2, typically leaving behind a functional homozygous viable hT2 with Bli-4 phenotype. |
| WS2277 |
hus-1(op241) I. |
C. elegans |
Maintain at 15 or 20C. Mrt at 25C. Defective for DNA damage induced germ cell death and cell cycle arrest. |
| WS2972 |
gla-3(op216) I. |
C. elegans |
Sterile or nearly sterile. Extra programmed cell death in germline. Maintain at 20 C. Reference: Kritikou et al. 2006 Genes Dev 20(16):2279-92. |
| WS2973 |
gla-3(op212) I. |
C. elegans |
Sterile or nearly sterile. Extra programmed cell death in germline. Maintain at 20 C. Reference: Kritikou et al. 2006 Genes Dev 20(16):2279-92. |
| WS2974 |
gla-3(ep312) I. |
C. elegans |
Sterile or nearly sterile. Extra programmed cell death in germline. Maintain at 20 C. Reference: Kritikou et al. 2006 Genes Dev 20(16):2279-92. |
| WS3403 |
opIs170. |
C. elegans |
opIs170 [sdn-1p::sdn-1::GFP::unc-54 3'UTR + lin-15(+)]. lin-15B(n765) might be present in background. GFP expression in neurons and hypodermis. Maintain under normal conditions. Reference: Rhiner C, et al. Development. 2005 Oct;132(20):4621-33. |
| WS3404 |
opIs171. |
C. elegans |
opIs171 [sdn-1p::sdn-1::GFP::unc-54 3'UTR + lin-15(+)]. lin-15B&lin-15A(n765) might be present in background. GFP expression in neurons and hypodermis. Maintain under normal conditions. Reference: Rhiner C, et al. Development. 2005 Oct;132(20):4621-33. |
| WS3455 |
chk-2(gk212) V. |
C. elegans |
|
| WS3530 |
mtm-1(op309) I. |
C. elegans |
|
| WS4274 |
unc-119(ed3) III; opIs206. |
C. elegans |
opIs206 [hif-1p::hif-1(genomic)::GFP::hif-1 3'UTR + unc-119(+)]. Weak GFP signal in early embryonic stages (2-cell, 4-cell, 8-cell, etc.). Reference: Sendoel A, et al. Nature. 2010 Jun 3;465(7298):577-83. |
| WS4543 |
opIs257. |
C. elegans |
opIs257 [rad-54p::rad-54::YFP::rad-54 3'UTR + unc-119(+)]. |
| WS4581 |
unc-119(ed3) III; opIs263. |
C. elegans |
opIs263 [rpa-1p::rpa-1::YFP + unc-119(+)]. YFP expression in soma and germline. |
| WS4591 |
unc-130(op459) II; hse-5(tm472) III. |
C. elegans |
|
| WS4700 |
opIs295 II; unc-119(ed3) III. |
C. elegans |
opIs295 [cdc-42p::GFP::cdc-42(genomic)::cdc-42 3'UTR + unc-119(+)] II. |
| WS4918 |
opIs310. |
C. elegans |
opIs310 [ced-1p::YFP::act-5::let-858 3'UTR + unc-119(+)]. |
| WS4920 |
ced-2(n1994) IV; opIs310. |
C. elegans |
opIs310 [ced-1p::YFP::act-5::let-858 3'UTR + unc-119(+)]. |
| WS5018 |
cdc-42(gk388) opIs295 II. |
C. elegans |
opIs295 [cdc-42p::GFP::cdc-42(genomic)::cdc-42 3'UTR + unc-119(+)] II. opIs295 fully rescues cdc-42 animals. |
| WS5229 |
unc-119(ed3) III; fan-1(tm423) IV; opIs406. |
C. elegans |
opIs406 [fan-1p::fan-1::GFP::let-858 3'UTR + unc-119(+)]. opIs406 resuces tm423. Reference: Kratz K, et al. Cell. 2010 Jul 9;142(1):77-88. |
| WS841 |
ptp-2(op194) unc-4(e120)/mIn1 [dpy-10(e128)] II; him-5(e1490) V. |
C. elegans |
Heterozygotes are WT and segregate WT, Uncs which are sterile (>10 offspring) and Dpys. Throws males of all classes. mIn1 pka mC6. |