Laboratory Information

NameWHY View on WormBase
Allele designationhow
HeadWen Tang
InstitutionThe Ohio State University
Address 1060 Carmack Road
Rightmire Hall Room 218
Columbus 43210
United States
Gene classes

Strains contributed by this laboratory

Strain Genotype Species Description
WHY10 glh-1(how3[3xHA::TurboID::glh-1]) I. C. elegans 3xHA::TurboID tag inserted at the N-terminus of the endogenous GLH-1. TurboID::GLH-1 promiscuously labels proteins at 20C. Transgene generated in N2 background. Reference: Price I, et al. ELife. 2021 Nov 3;10:e72276. doi: 10.7554/eLife.72276.
WHY8 Cbr-prg-1(how21) I. C. briggsae C. briggsae strain. Reduced fecundity at 20°C and 25°C. Generated by CRISPR/Cas9 in AF16 background, prg-1(how21) is a 5 bp deletion located 47 bp downstream of the start codon that causes frameshift. prg-1(how21) is presumed null; consistent with previous findings that the stability of piRNAs and Piwi protein are co-dependent in C. elegans, the overall abundance of 21 U-RNAs in Cbr-prg-1(how21) was reduced to ~1% of wild-type. Reference: Pastore B, et al. RNA Biol. 2022 Jan;19(1):1276-1292. doi: 10.1080/15476286.2022.2149170.
This laboratory hasn't submitted any alleles to the CGC.