Laboratory Information
| Name | WHY View on WormBase |
|---|---|
| Allele designation | how |
| Head | Wen Tang |
| Institution | The Ohio State University |
| Address | 1060 Carmack Road Rightmire Hall Room 218 Columbus 43210 United States |
| Gene classes |
Strains contributed by this laboratory
| Strain | Genotype | Species | Description |
|---|---|---|---|
| WHY10 | glh-1(how3[3xHA::TurboID::glh-1]) I. | C. elegans | 3xHA::TurboID tag inserted at the N-terminus of the endogenous GLH-1. TurboID::GLH-1 promiscuously labels proteins at 20C. Transgene generated in N2 background. Reference: Price I, et al. ELife. 2021 Nov 3;10:e72276. doi: 10.7554/eLife.72276. |
| WHY8 | Cbr-prg-1(how21) I. | C. briggsae | C. briggsae strain. Reduced fecundity at 20°C and 25°C. Generated by CRISPR/Cas9 in AF16 background, prg-1(how21) is a 5 bp deletion located 47 bp downstream of the start codon that causes frameshift. prg-1(how21) is presumed null; consistent with previous findings that the stability of piRNAs and Piwi protein are co-dependent in C. elegans, the overall abundance of 21 U-RNAs in Cbr-prg-1(how21) was reduced to ~1% of wild-type. Reference: Pastore B, et al. RNA Biol. 2022 Jan;19(1):1276-1292. doi: 10.1080/15476286.2022.2149170. |
This laboratory hasn't submitted any alleles to the CGC.