Laboratory Information
| Name | VB View on WormBase |
|---|---|
| Allele designation | sv |
| Head | Simon Patrick Tuck |
| Institution | Umea University, Vasterbotten, Sweden |
| Address | Umea University UCMM Johan Bures väg 12 Umea SE-901 87 Sweden |
| Website | http://www.ucmm.umu.se |
| Gene classes | asna gsr mlt num mtcu mttu |
Strains contributed by this laboratory
| Strain | Genotype | Species | Description |
|---|---|---|---|
| GS445 | lin-25(ar90) V/nT1 [unc-?(n754) let-?] (IV;V). | C. elegans | Heterozygotes are Unc and segregate Uncs, dead eggs, and Egl. lin-25(ar90) is a probable null mutation. Hermaphrodites are completely unable to lay eggs. Lineage defects in VPCs. Amber mutation (codon 197); amber suppressable. Do not distribute this strain; other labs should request it from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects. |
| GS528 | lin-25(sy29) V/nT1 [unc-?(n754) let-?] (IV;V). | C. elegans | Heterozygotes are Unc and segregate Uncs, dead eggs, and Egl. lin-25(sy29) is a non-null allele. Hermaphrodites are 100% Egl but some eggs are seen on plates. Results from a missense mutation in codon 103. Do not distribute this strain; other labs should request it from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects. |
| VB1050 | maa-1(sv37) III. | C. elegans | |
| VB1174 | asna-1(sv42) III/hT2 [bli-4(e937) let-?(q782) qIs48] (I;III). | C. elegans | Homozygous lethal mutation balanced by bli-4- and GFP-marked translocation. Heterozygotes are WT with pharyngeal GFP signal, and segregate WT GFP, arrested hT2 aneuploids, and non-GFP sv42 homozygotes (scrawny, arrests late larva or sterile adult). Homozygous hT2[bli-4 let-? qIs48] inviable. Note: qIs48 has been observed to recombine off hT2, typically leaving behind a functional homozygous viable hT2 with Bli-4 phenotype. Pick WT GFP and check for correct segregation of progeny to maintain. Attribution: This strain was provided by the C. elegans Reverse Genetics Core Facility at the University of British Columbia, which is part of the international C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use. Paper_evidence WBPaper00041807 |
| VB1336 | nnt-1(tm358) X. | C. elegans | Sensitive to oxidative stress. |
| VB674 | nnt-1(sv34) X. | C. elegans | Sensitive to oxidative stress. |
Alleles contributed by this laboratory
| Allele | Type | DNA Change | Protein Change |
|---|---|---|---|
| sv32 | Allele | deletion | |
| sv15 | Allele | substitution | splice_site |
| sv30 | Allele | deletion | |
| sv37 | Allele | deletion | |
| sv42 | Allele | deletion | |
| sv34 | Allele | deletion | |
| sv47 | Allele | deletion |