Laboratory Information

NameSSR View on WormBase
Allele designationssr
HeadSupriya Srinivasan
InstitutionScripps Research Inst, La Jolla, CA
Address The Scripps Research Institute
DNC 208
9365 Waples St., Suite E
San Diego 92121
United States
Website http://www.scripps.edu/chemphys/srinivasan/Srinivasan_Lab_Website/Home.html
Gene classes

Strains contributed by this laboratory

Strain Genotype Species Description
SSR1070 mzmEx291. C. elegans mzmEx291 [flp-8p::GCaMP5k + flp-8p::mCherry]. Pick mCherry+ animals to maintain. URX-neuron-specific expression of GCaMP5k and mCherry. Reference: Hussey R, et al. PLoS Genet. 2018 14(3): e1007305. doi: 10.1371/journal.pgen.1007305. PMID: 29579048.
SSR1164 ssrIs919; ssrIs615. C. elegans ssrIs919 [daf-7p::flp-7::mCherry]. ssrIs615 [unc-122p::GFP]. Strain can be used for FLP-7 peptide secretion assays. Reference: Palamiuc L,. et al. Nat Commun. 2017 Jan 27:8:14237. doi: 10.1038/ncomms14237. PMID: 28128367.
SSR1530 ssrIs1222; ssrIs1031. C. elegans ssrIs1222 [hlh-11p::hlh-11::GFP]. ssrIs1031 [myo-2p::mCherry]. Translational hlh-11::GFP reporter. Reference: Littlejohn NK, et al. Elife 2020 Oct 20:9:e58815. doi: 10.7554/eLife.58815. PMID: 33078707.
SSR1578 ssrIs1248. C. elegans ssrIs1248 [ges-1p(deltaB)::rpl-22::3xHA + ges-1p(deltaB)::GFP + pSM(empty vector)]. ges-1p(deltaB) is an INT1-specific promoter. Strain can be used for INT1-specific RiboTRAP experiments. Generated in N2 background. Reference: Liu C, et al. bioRxiv 2025.10.03.680215; doi: https://doi.org/10.1101/2025.10.03.680215
SSR1605 ssrIs1251. C. elegans ssrIs1251 [pho-1p::rpl-22::3xHA + pho-1p::mCherry + pSM(empty vector)]. pho-1p is an INT2-9-specific promoter. Strain can be used for INT2-9-specific RiboTRAP experiments. Generated in N2 background. Reference: Liu C, et al. bioRxiv 2025.10.03.680215; doi: https://doi.org/10.1101/2025.10.03.680215
SSR1617 ssrIs1240; ssrIs615. C. elegans ssrIs1240 [ges-1p(deltaB)::ins-7::mCherry]. ssrIs615 [unc-122p::GFP]. The INS-7::mCherry fusion protein localizes in GFP-labeled coelomocytes. ges-1p(deltaB) is an INT1-specific promoter. Reference: Liu CC, et al. Nat Commun. 2024 Aug 11;15(1):6869. doi: 10.1038/s41467-024-51077-3. PMID: 39127676.
SSR1621 ins-7(ssr1532) IV. C. elegans Null allele. ins-7(ssr1532) is a CRISPR-engineered deletion that removes the second exon of ins-7 and introduces stop codons. Reference: Liu CC, et al. Nat Commun. 2024 Aug 11;15(1):6869. doi: 10.1038/s41467-024-51077-3. PMID: 39127676.
SSR647 ssrIs496. C. elegans ssrIs496 [atgl-1p::GFP + rol-6(su1006)]. Rollers. Transcriptional atgl-1::GFP reporter. Reference: Noble T, et al. Cell Metab. 2013 Nov 5;18(5):672-84. doi: 10.1016/j.cmet.2013.09.007. PMID: 24120942.
This laboratory hasn't submitted any alleles to the CGC.