Laboratory Information
| Name | QW View on WormBase |
|---|---|
| Allele designation | zf |
| Head | Alkema, Mark |
| Institution | University of Massachusetts Chan Medical School, Worcester, MA |
| Address | 364 Plantation Street, LRB 717 Department of Neurobiology, University of Massachusetts Medical School Worcester 01605 United States |
| Website | http://www.umassmed.edu/neurobiology/faculty/Alkema.cfm?start=0& |
| Gene classes |
Strains contributed by this laboratory
| Strain | Genotype | Species | Description |
|---|---|---|---|
| QW1075 | lite-1(ce314) X; zdIs5; zfEx416. | C. elegans | zdIs5 [mec-4p::GFP + lin-15(+)] I. zfEx416 [rig-3p::GFP::SL2::mCherry]. Pick animals with red fluorescence to maintain zfEx416. Reference: Shipley FB, et al. Front Neural Circuits. 2014 Mar 24;8:28. |
| QW1655 | lin-15B&lin-15A(n765) zfIs149 X. | C. elegans | zfIs149 [flp-18p(3kb)::mCherry::SL2::FLP-18 + lin-15(+)] X. FLP-18 expressing neurons are labeled with cytosolic mCherry. Overexpression of FLP-18 causes uncoordinated locomotion. Animals exhibit exaggerated head and body bends, increased reversal frequency, and enhanced calcium transients in body-wall muscle. These phenotypes are suppressed by loss of NPR-5. Reference: Florman JT & Alkema MJ. PLOS Genet. 2022 Mar 3;18(3):e1010091. doi: 10.1371/journal.pgen.1010091. PMID: 35239681. |
| QW309 | zfIs18. | C. elegans | zfIs18 [mec-4p::ChR2::YFP + lin-15(+)]. Reference: Shipley FB, et al. Front Neural Circuits. 2014 Mar 24;8:28. |
| QW625 | zfIs42. | C. elegans | zfIs42 [rig-3p::GCaMP3::SL2::mCherry + lin-15(+)]. Reference: Shipley FB, et al. Front Neural Circuits. 2014 Mar 24;8:28. |
This laboratory hasn't submitted any alleles to the CGC.