Laboratory Information

NamePR View on WormBase
Allele designationp
Head
Institution University of Pittsburgh, PA
Address

Gene classes ace  cha 

Strains contributed by this laboratory

Strain Genotype Species Description
PR1152 cha-1(p1152) IV. C. elegans Structural gene for choline acetyltransferase (ChAT). Slow growing. Unc-coils, jerky going backward. Small. Resistant to aldicarb and trichlorfon. 99% reduced choline acetyltransferase. Complex complementation pattern with unc-17.
PR1162 cha-1(p503) IV. C. elegans Mild (leaky) allele of cha-1. Has approximately 10% WT ChAT activity. Behaviorally normal-normal growth and development. Males mate. Sensitive to cholinesterase inhibitor aldicarb.
PR671 tax-2(p671) I. C. elegans Defective in chemotaxis to Na+, Cl-, OH-, NaHCO3, pyridine, cAMP, D-tryptophan, CO2(phosphate). Partially defective in chemotaxis to H+(phosphate). Slightly inverted taxis to H+(citrate). Thermotaxis defective too.
PR672 che-1(p672) I. C. elegans Defective in chemotaxis to Na+, OH-, NaHCO3; partially defective in chemotaxis to CL-; inverted taxis to cAMP.
PR673 hsp-90(p673) V. C. elegans Defective in chemotaxis to all attractants and to D-tryptophan; partially defective in chemotaxis to CO2(phosphate) and H+(citrate). Thermotaxis weak. p673 previously called tax-3 or daf-21.
PR674 che-1(p674) I. C. elegans Defective in chemotaxis to all attractants except pyridine and D-tryptophan. Thermotaxis okay.
PR675 tax-6(p675) IV. C. elegans Defective in chemotaxis to Na+, Cl-, OH-, NaHCO3, pyridine, cAMP, D-tryptophan; partially defective to CO2(phosphate), H+(phosphate), H+(citrate); a little Small. Thermotaxis is funny.
PR678 tax-4(p678) III. C. elegans Defective in chemotaxis to Na+, NaHCO3, pyridine, cAMP, D-tryptophan; partially defective to CO2(phosphate)m H+(phosphate),, H+(citrate); inverted taxis to Cl-, OH-. Progeny yield about 50% of normal. No Thermotaxis. See also WBPaper00002585.
PR679 che-1(p679) I. C. elegans Defective in chemotaxis to all attractants except pyridine and D-tryptophan. Thermotaxis okay. 1/2007: new stock received from Michael Ailion due to a recent Dyf mutation appearing in the old CGC stock.
PR680 che-1(p680) I. C. elegans Defective in chemotaxis to all attractants except pyridine and D-tryptophan. Thermotaxis okay.
PR691 tax-2(p691) I. C. elegans Defective in chemotaxis to all attractants and to D-tryptophan. Thermotaxis defective.
PR692 che-1(p692) I. C. elegans Defective in chemotaxis to all attractants except pyridine and D-tryptophan. Partial defects in taxis to pyridine, H+(phosphate) and H+(citrate).
PR694 tax-2(p694) I. C. elegans Defective in chemotaxis to everything except pyridine. Thermotaxis is weak.
PR696 che-1(p696) I. C. elegans Defective in chemotaxis to all attractants except D-tryptophan. Partially defective in response to pyridine, H+(citrate). Thermotaxis okay.

Alleles contributed by this laboratory

Allele Type DNA Change Protein Change
p694 Allele deletion
p671 Allele substitution
p678 Allele substitution nonsense
p1000 Allele substitution nonsense
p672 Allele substitution nonsense
p674 Allele substitution nonsense
p675 Allele substitution
p679 Allele substitution nonsense
p680 Allele substitution nonsense
p691 Allele substitution
p692 Allele substitution
p696 Allele substitution
p767 Allele substitution splice_site
p802 Allele substitution nonsense
p811 Allele substitution splice_site
p813 Allele substitution nonsense
p816 Allele deletion
p821 Allele substitution splice_site
p1001 Allele substitution